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Ack1 inhibitor 1

CAT: 0013-GTR19235709-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235709-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ack1 inhibitor 1 is a potent, selective, and orally bioavailable small molecule targeting ACK1 kinase with an IC50 of 2.1 nM. It blocks ACK1 autophosphorylation and downstream AKT signaling, showing anti-proliferative effects in cellular assays and demonstrating in vivo efficacy in xenograft tumor models.
CAS Number
2924415-92-7
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (N1C=2C (C=C (C1=O) C3=CC (NC (=O) C4=CC (C (F) (F) F) =CC=C4) =CC=C3) =CN=C (NC5=C (OCC) C=C (C=C5) N6CCN (C) CC6) N2) [C@H]7CCCO7
Molecular Formula
C39H40F3N7O4
Molecular Weight
727.77
Storage Conditions
-20°C
Notes
For research use only.

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