Anti-ACK1

• Description:

  This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinic GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.

• Reactivity:

  Human,Mouse

• Immunogen:

  A peptide corresponding to amino acids 278-289 of ACK1 protein.

• Clonality:

  Polyclonal

• Type:

  Antibodies-Polyclonal

• Applications:

  WB,ELISA

• Concentration:

  100ug/100ul

• Purity:

  Purified

• Buffer:

  PBS, pH 7.4 with 0.02% Sodium Azide

• Shipping Conditions:

  Ice Pack

• Storage Conditions:

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment:

  Rabbit IgG

• Specificity:

  Not tested with other proteins

• Applications Notes:

  Recommended dilutions Peptide ELISA: 1:16,000 WB: 1/500 - 1/1000. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user

• CAS Number:

  9007-83-4