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E3 ligase Ligand 21

CAT: 0013-GTR19235460-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235460-01Size:10 mg
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Description
E3 Ligase Ligand 21 (compound 2) is a cereblon-binding molecular glue that induces ubiquitination and proteasomal degradation of Ikaros and Aiolos. This mechanism of action makes it a valuable chemical probe for targeted protein degradation research in both cellular and preclinical models of hematological malignancies.
CAS Number
2504233-73-0
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Smiles
O=C1C2=CC=CC=3C (=CC=C (C23) N1C4C (=O) NC (=O) CC4) CC=5C=NN (C5) C6CCN (CC6) CC7 (C) CCC7
Molecular Formula
C31H35N5O3
Molecular Weight
525.64
Storage Conditions
-20°C
Notes
For research use only.

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