Products for Research Use Only

MTX115325

CAT: 0013-GTR19234945-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234945-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MTX115325 is a potent, orally bioavailable, and brain-penetrant USP30 inhibitor (IC50=12 nM) that induces mitophagy by enhancing TOM20 ubiquitination (EC50=32 nM) . It demonstrates neuroprotective efficacy in research models, preventing dopaminergic neuron loss and preserving striatal dopamine levels in vivo.
CAS Number
2750895-97-5
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry
Smiles
C (=O) (N1[C@@]2 ([C@@] ([C@@H] (C) N (C#N) C2) (CC1) [H]) [H]) C=3OC (=CN3) C=4C=C (C#N) N=CC4
Molecular Formula
C18H16N6O2
Molecular Weight
348.36
Storage Conditions
-20°C
Notes
For research use only.

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