Products for Research Use Only

P-gp inhibitor 27

CAT: 0013-GTR19241498-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241498-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P-gp inhibitor 27 (Compound D2) is a small molecule that suppresses P-glycoprotein and MRP1 expression. It enhances Rh123 accumulation in resistant A2780/T cells and effectively reverses multidrug resistance to Paclitaxel and Cisplatin in vitro, with an EC50 of 88 nM against Paclitaxel.
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Molecular Formula
C25H25N3O4
Molecular Weight
431.48
Storage Conditions
-20°C
Notes
For research use only.