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AGU654

CAT: 0013-GTR19241462-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241462-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AGU654 (Compound 44) is a potent and selective mPGES-1 inhibitor (IC50 = 2.9 nM) that suppresses PGE2 production in vitro in human macrophages and whole blood, and demonstrates anti-inflammatory, analgesic, and antipyretic efficacy in guinea pig models, supporting its use for researching inflammatory diseases and pain.
CAS Number
3038861-74-1
Field of Research
Immunology & Inflammation
Smiles
O=C (NC=1C=CC (=CC1) C2=NC3=CC=C (C=C3N2) C (F) (F) F) C4=CC (=CC=C4Cl) CNC (=O) C5 (CC5) C (F) (F) F
Molecular Formula
C27H19ClF6N4O2
Molecular Weight
580.91
Storage Conditions
-20°C
Notes
For research use only.

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