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(R) -SR-C-107

CAT: 0013-GTR19241372-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241372-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) -SR-C-107 is a potent, orally bioavailable small molecule inhibitor targeting the ENL YEATS domain for acute myeloid leukemia (AML) research. It exhibits an IC50 of 40 nM and a KD of 144 nM against ENL. In an AML xenograft model, oral administration (200 mg/kg, QD) induced 45% tumor regression, demonstrating significant in vivo efficacy.
Field of Research
Epigenetics & Chromatin
Molecular Formula
C21H23N7O
Molecular Weight
389.45
Storage Conditions
-20°C
Notes
For research use only.

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