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SR 1078

CAT: 0013-GTR19159740-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159740-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SR-1078 is a selective agonist of RORα and RORγ that stimulates ROR transcriptional activity in HEK293 cell reporter assays at concentrations as low as 2 μM without effect at the related liver X receptors and farnesoid X receptors. SR1078 modulates the conformation of RORγ in a biochemical assay and activates RORα and RORγ driven transcription. SR1078 stimulates expression of endogenous ROR target genes in HepG2 cells that express both RORα and RORγ. SR1078 can be utilized as a chemical tool to probe the function of these receptors both in vitro and in vivo.
CAS Number
1246525-60-9
Product Name Alternative
SR-1078 | SR 1078 | SR1078
Purity
>98% (HPLC)
Solubility
DMSO : 33.33 mg/mL 77.29 mM
Smiles
OC (c1ccc (NC (=O) c2ccc (cc2) C (F) (F) F) cc1) (C (F) (F) F) C (F) (F) F
Molecular Formula
C17H10F9NO2
Molecular Weight
431.25
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (4- (1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl) phenyl) -4- (trifluoromethyl) benzamide

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