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CSF1R-IN-22

CAT: 0013-GTR19235542-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235542-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CSF1R-IN-22 is a potent and selective CSF-1R inhibitor that reprograms M2 macrophages to an M1 phenotype, enhancing CXCL9 secretion and CD8+ T cell infiltration in the tumor microenvironment. It demonstrates synergistic anti-tumor activity with anti-PD-1 therapy in preclinical models, reducing immunosuppressive cell populations like Tregs and MDSCs.
CAS Number
2760585-35-9
Field of Research
Cell Biology, Signal Transduction
Smiles
C (=C\1/C=2C (=CC (NC (NC=3C=C (C (C) (C) C) ON3) =O) =CC2) NC1=O) \C4=CN=CN4
Molecular Formula
C20H20N6O3
Molecular Weight
392.41
Storage Conditions
-20°C
Notes
For research use only.

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