Products for Research Use Only

Tuspetinib hydrate

CAT: 0013-GTR19235190-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235190-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tuspetinib hydrate is a potent, orally available, and selective type I FLT3 inhibitor with low nM IC50 values against FLT3 WT, ITD, and D835Y mutants. It disrupts key signaling pathways (e.g., STAT5, ERK) and has demonstrated activity in inhibiting proliferation and inducing apoptosis in FLT3-mutant leukemia cells in preclinical studies.
CAS Number
2758339-04-5
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
ClC=1C (C=2C=3C (NC2) =CC (C) =CC3) =NC (NC4=CC (=CC (CN5C[C@@H] (C) N[C@@H] (C) C5) =C4) C6CC6) =NC1.O
Molecular Formula
C29H35ClN6O
Molecular Weight
519.08
Storage Conditions
-20°C
Notes
For research use only.