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KH-4-43

CAT: 0013-GTR19232640Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19232640Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KH-4-43 is a potent and selective inhibitor of the CRL4 E3 ubiquitin ligase complex, binding its ROC1-CUL4A core with high affinity (Kd = 83 nM) . This small molecule is a valuable research tool for investigating CRL4 function in cancer biology and has demonstrated anticancer activity in cellular assays.
CAS Number
2813310-07-3
Field of Research
Protein Biochemistry
Smiles
C (F) (F) (F) C1=C (C (=O) C=2C (O1) =C (O) C (O) =CC2) C3=CN (N=C3) C4=CC=C (Cl) C=C4
Molecular Formula
C19H10ClF3N2O4
Molecular Weight
422.74
Storage Conditions
-20°C
Notes
For research use only.

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