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DBCO-PEG4-GGFG-Dxd

CAT: 0013-GTR19232589-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19232589-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DBCO-PEG4-GGFG-Dxd is a cleavable linker-payload conjugate for constructing antibody-drug conjugates (ADCs) . Its DBCO group enables efficient bioconjugation via click chemistry with azide-modified antibodies, delivering the topoisomerase I inhibitor Dxd to target cells. This construct is utilized in oncology research for evaluating potent antitumor activity in both in vitro and in vivo models.
CAS Number
2694856-51-2
Field of Research
Molecular Biology
Purity
96.58% (May vary between batches)
Smiles
N (C (COCNC (CNC ([C@H] (CC1=CC=CC=C1) NC (CNC (CNC (CCOCCOCCOCCOCCNC (CCC (=O) N2C=3C (C#CC=4C (C2) =CC=CC4) =CC=CC3) =O) =O) =O) =O) =O) =O) =O) [C@@H]5C6=C7C (C=8N (C7) C (=O) C9=C (C8) [C@] (CC) (O) C (=O) OC9) =NC=%10C6=C (CC5) C (C) =C (F) C%10
Molecular Formula
C72H79FN10O17
Molecular Weight
1375.45
Storage Conditions
-20°C
Notes
For research use only.

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