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DIBAC-GGFG-NH2CH2-Dxd

CAT: 0013-GTR19232563Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19232563Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DIBAC-GGFG-NH2CH2-Dxd (LP4) is a camptothecin-derived linker-payload featuring a DBCO group for click chemistry conjugation via SPAAC. It serves as the cytotoxic warhead in the ADC DS-8201a (Enhertu) and is a key reagent for constructing bioconjugates for targeted drug delivery research in both in vitro and in vivo models.
CAS Number
2758875-01-1
Smiles
N (C (COCNC (CNC ([C@H] (CC1=CC=CC=C1) NC (CNC (CNC (CCC (=O) N2C=3C (C#CC=4C (C2) =CC=CC4) =CC=CC3) =O) =O) =O) =O) =O) =O) [C@@H]5C6=C7C (C=8N (C7) C (=O) C9=C (C8) [C@] (CC) (O) C (=O) OC9) =NC=%10C6=C (CC5) C (C) =C (F) C%10
Molecular Formula
C61H58FN9O12
Molecular Weight
1128.16
Storage Conditions
-20°C
Notes
For research use only.

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