Phenylephrine (Standard)

• Description:

  Phenylephrine (Standard) is the analytical standard of Phenylephrine. This product is intended for research and analytical applications. (R) - (-) -Phenylephrine is a selective α1-adrenoceptor agonist primarily used as a decongestant.

• Product Name Alternative:

  (R) - (-) -Phenylephrine (Standard) ; L-Phenylephrine (Standard)

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H318, H335

• Target:

  Adrenergic Receptor; Reference Standards

• Type:

  Reference Standards

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling; Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cardiovascular Disease; Endocrinology; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/phenylephrine-standard.html

• Purity:

  99.96

• Smiles:

  O[C@H](C1=CC(O)=CC=C1)CNC

• Molecular Formula:

  C9H13NO2

• Molecular Weight:

  167.21

• Precautions:

  H302, H315, H318, H335

• References & Citations:

  [1]Ford AP, et al. Pharmacological pleiotropism of the human recombinant alpha1A-adrenoceptor: implications foralpha1-adrenoceptor classification. Br J Pharmacol. 1997 Jul;121 (6) :1127-35.|[2]Minneman KP, et al. Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes. Mol Pharmacol. 1994 Nov;46 (5) :929-36.|[3]Wang J, et al. Phenylephrine promotes cardiac fibroblast proliferation through calcineurin-NFAT pathway. Front Biosci (Landmark Ed) . 2016 Jan 1;21:502-13.|[4]Lazou A, et al. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart. Biochem J. 1998 Jun 1;332 (Pt 2) :459-65.|[5]Li NJ, et al. Effect of phenylephrine on alveolar fluid clearance in ventilator-induced lung injury. Chin Med Sci J. 2013 Mar;28 (1) :1-6.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  4°C, sealed storage, away from light and moisture

• Scientific Category:

  Reference Standards

• CAS Number:

  [59-42-7]