Phenylephrine (Standard)

• UNSPSC Description:

  Phenylephrine (Standard) is the analytical standard of Phenylephrine. This product is intended for research and analytical applications. (R)-(-)-Phenylephrine is a selective α1-adrenoceptor agonist primarily used as a decongestant.

• Target Antigen:

  Adrenergic Receptor

• Type:

  Reference Standards

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Cardiovascular Disease; Endocrinology; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/phenylephrine-standard.html

• Smiles:

  O[C@H](C1=CC(O)=CC=C1)CNC

• Molecular Weight:

  167.21

• References & Citations:

  [1]Ford AP, et al. Pharmacological pleiotropism of the human recombinant alpha1A-adrenoceptor: implications foralpha1-adrenoceptor classification. Br J Pharmacol. 1997 Jul;121(6):1127-35.|[2]Minneman KP, et al. Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes. Mol Pharmacol. 1994 Nov;46(5):929-36.|[3]Wang J, et al. Phenylephrine promotes cardiac fibroblast proliferation through calcineurin-NFAT pathway. Front Biosci (Landmark Ed). 2016 Jan 1;21:502-13.|[4]Lazou A, et al. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart. Biochem J. 1998 Jun 1;332 ( Pt 2):459-65.|[5]Li NJ, et al. Effect of phenylephrine on alveolar fluid clearance in ventilator-induced lung injury. Chin Med Sci J. 2013 Mar;28(1):1-6.

• Shipping Conditions:

  Room temperature

• CAS Number:

  59-42-7