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H3B-968

CAT: 0013-GTR19230803-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230803-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
H3B-968 is a potent, ATP-competitive inhibitor of the Werner syndrome helicase (WRN), exhibiting an IC50 of ~10 nM against its helicase activity. This small molecule is a valuable research tool for investigating synthetic lethality in microsatellite unstable (MSI) cancer models, both in cellular and in vivo studies.
CAS Number
2912294-90-5
Field of Research
Cell Biology, Molecular Biology
Smiles
S (NCC (NC1=CC=C (CC) C=C1) =O) (=O) (=O) C=2N=C (C=C (C (F) (F) F) N2) C3=CC=C (OC (F) (F) F) C=C3
Molecular Formula
C22H18F6N4O4S
Molecular Weight
548.46
Storage Conditions
-20°C
Notes
For research use only.

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