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PROTAC α-synuclein degrader 5

CAT: 0013-GTR19230598Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230598Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This potent and selective PROTAC degrader targets α-synuclein aggregates with a DC50 of 7.51 μM and a Dmax of 89%. Its design, incorporating the sery308 probe and E3 ligase ligands, makes it a valuable chemical tool for investigating α-synuclein pathology in cellular and in vivo models of Parkinson's disease and related synucleinopathies.
CAS Number
2781922-42-5
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2NCCOCCOCCOCCNC (CNC4=CC (=CC=C4) C=5C=C (NN5) C=6C=C7C (=CC6) OCO7) =O
Molecular Formula
C39H41N7O10
Molecular Weight
767.78
Storage Conditions
-20°C
Notes
For research use only.

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