Products for Research Use Only

VHL-IN-1

CAT: 0013-GTR19230322-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230322-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VHL-IN-1 is a potent VHL E3 ligase inhibitor with a 37 nM Kd, effectively stabilizing HIF-1α and augmenting its transcriptional function. This small molecule is a valuable chemical probe for hypoxia research and serves as a foundational component for developing PROTAC degraders in both cellular and animal studies.
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C28H37FN4O4S
Molecular Weight
544.68
Storage Conditions
-20°C
Notes
For research use only.