DASK1-VHL

• Target:

  PROTACs|||ASK|||p38 MAPK

• Related Pathways:

  PROTAC|||Apoptosis|||MAPK

• Bioactivity:

  DASK1-VHL is an orally active PROTAC degrader targeting ASK1. It effectively binds to VHL, promoting the selective degradation of ASK1. By reducing ASK1 protein levels, dASK1-VHL inhibits the activation of p38 MAPK and decreases liver lipid content, offering new insights for MASH research.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C