Products for Research Use Only

PKM2-IN-6

CAT: 0013-GTR19234764-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234764-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PKM2-IN-6 (7d) is a potent, orally bioavailable PKM2 inhibitor with an IC50 of 23 nM. It downregulates PKM1/2 mRNA, induces apoptosis and G2/M arrest, and demonstrates antitumor activity in preclinical models, making it a valuable tool for studying triple-negative breast cancer (TNBC) in both cellular and animal studies.
CAS Number
771467-00-6
Field of Research
Cell Biology, Metabolism Research
Purity
99.83% (May vary between batches)
Solubility
DMSO:100 mg/mL (310.19 mM)
Smiles
N (C1=NC (C=2N3C (=NC2) C=CC=C3) =CS1) C4=C (OC) C=CC=C4
Molecular Formula
C17H14N4OS
Molecular Weight
322.38
Storage Conditions
-20°C
Notes
For research use only.