Simvastatin acid-d3 (ammonium)

• UNSPSC Description:

  Simvastatin acid-d3 (Tenivastatin-d3) ammonium is deuterium-labeled Simvastatin acid (ammonium) (HY-119695A)[1].

• Target Antigen:

  HMG-CoA Reductase (HMGCR); Isotope-Labeled Compounds; Reactive Oxygen Species

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C(C[C@@H](C[C@@H](CC[C@H]1[C@H](C=CC2=C[C@@H](C[C@@H]([C@]12[H])OC(C(C)(CC)C([2H])([2H])[2H])=O)C)C)O)O)[O-].[NH4+]

• Molecular Weight:

  456.63

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Smith K A, et al. Soil and environmental analysis[M]. Marcel Dekker Incorporated, 2000.|[3]Fan T W M, et al. Stable isotope-resolved metabolomics and applications for drug development[J]. Pharmacology & therapeutics, 2012, 133(3): 366-391.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported