Lactimidomycin

CAT: 0013-GTR19226475Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19226475Size:1 mg

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Description

Lactimidomycin is a Streptomyces-derived small molecule that potently inhibits eukaryotic translation elongation, exhibiting antiviral activity against dengue virus 2 and antiproliferative effects in tumor cell lines. Its primary application is in researching protein synthesis inhibition, with an IC50 of 37.82 nM, supporting both in vitro virology and oncology studies.

CAS Number

134869-15-1

Field of Research

Infectious Disease & Virology

Smiles

C ([C@H] (CC ([C@H] (/C=C (\C) /[C@H]1[C@@H] (C) \C=C/C=C/CC\C=C\C (=O) O1) C) =O) O) C2CC (=O) NC (=O) C2

Molecular Formula

C26H35NO6

Molecular Weight

457.56

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

Lactimidomycin

Lactimidomycin has been reported in Streptomyces amphibiosporus with data available.

CAS Number	134869-15-1
PubChem CID	139586089
IUPAC Name	4-[(E,2R,5S)-2-hydroxy-5-methyl-7-[(3S,4Z,6E,10E)-3-methyl-12-oxo-1-oxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-enyl]piperidine-2,6-dione
Molecular Formula	C26H35NO6
Molecular Weight	457.6
XLogP	3.2
Topological Polar Surface Area	110
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	7
Heavy Atom Count	33
Formal Charge	0
Complexity	837

SMILES

C[C@H]1/C=C\C=C\CC/C=C/C(=O)OC1/C(=C/[C@H](C)C(=O)C[C@@H](CC2CC(=O)NC(=O)C2)O)/C

InChI

InChI=1S/C26H35NO6/c1-17-10-8-6-4-5-7-9-11-25(32)33-26(17)19(3)12-18(2)22(29)16-21(28)13-20-14-23(30)27-24(31)15-20/h4,6,8-12,17-18,20-21,26,28H,5,7,13-16H2,1-3H3,(H,27,30,31)/b6-4+,10-8-,11-9+,19-12+/t17-,18-,21+,26?/m0/s1

InChIKey

OYOKHBHOTQDIPM-UESXVERFSA-N

Chemical Structure

2D Structure

CAS: 134869-15-1

CID: 139586089

Formula: C26H35NO6

MW: 457.6

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	457.6
XLogP3	3.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	7
Exact Mass	457.24643784
Monoisotopic Mass	457.24643784
Topological Polar Surface Area	110 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	837
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	4
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
MBS5769270	Lactimidomycin

Lactimidomycin

Chemical Information

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