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Mal-PEG4-VA-PBD

CAT: 0013-GTR19225340-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19225340-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mal-PEG4-VA-PBD is a cleavable linker-payload conjugate designed for constructing Antibody-Drug Conjugates (ADCs) . It incorporates the potent DNA-crosslinking agent pyrrolobenzodiazepine (PBD), enabling targeted cytotoxicity. This conjugate is widely used in ADC research for evaluating antitumor efficacy in both in vitro and in vivo experimental models.
CAS Number
1342820-68-1
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
O=C1N2[C@@] (CC (=C2) C3=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCOCCOCCOCCOCCNC (CCN4C (=O) C=CC4=O) =O) =O) C (C) C) =O) C) =O) C=C3) (C=NC=5C1=CC (OC) =C (OCCCOC6=C (OC) C=C7C (=C6) N=C[C@]8 (N (C7=O) C=C (C8) C9=CC=C (OC) C=C9) [H]) C5) [H]
Molecular Formula
C68H79N9O17
Molecular Weight
1294.41
Storage Conditions
-20°C
Notes
For research use only.

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