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SPP-DM1

CAT: 0013-GTR19224945-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19224945-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SPP-DM1 is a cleavable linker-payload conjugate used in the development of antibody-drug conjugates (ADCs) . It incorporates the maytansinoid DM1, a potent antimitotic agent, to enable targeted cytotoxicity. This construct has demonstrated significant antitumor efficacy in both in vitro cell assays and in vivo xenograft models.
CAS Number
452072-20-7
Field of Research
Pharmacology & Drug Discovery
Smiles
[H][C@@]12C[C@@] (O) (NC (=O) O1) [C@] ([H]) (OC) \C=C/C=C (C) \Cc1cc (OC) c (Cl) c (c1) N (C) C (=O) C[C@] ([H]) (OC (=O) [C@H] (C) N (C) C (=O) CCSSC (C) CCC (=O) ON1C (=O) CCC1=O) [C@]1 (C) O[C@H]1[C@@H]2C
Molecular Formula
C44H59ClN4O14S2
Molecular Weight
967.54
Storage Conditions
-20°C
Notes
For research use only.

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