Products for Research Use Only

DM1-SMe

CAT: 0013-GTR19216557-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19216557-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DM1-SMe is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines.
CAS Number
138148-68-2
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (127.49 mM)
Smiles
CO[C@@H]1\C=C/C=C (C) /Cc2cc (OC) c (Cl) c (c2) N (C) C (=O) C[C@@H] (OC (=O) [C@H] (C) N (C) C (=O) CCSSC) [C@]2 (C) OC2[C@H] (C) [C@@H]2C[C@@]1 (O) NC (=O) O2
Molecular Formula
C36H50ClN3O10S2
Molecular Weight
784.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.