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Sulfo-SPDB-DM4

CAT: 0013-GTR19224936-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19224936-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sulfo-SPDB-DM4 is a cleavable linker-payload conjugate for constructing antibody-drug conjugates (ADCs) . It delivers the potent maytansinoid DM4, a microtubule-disrupting agent, to target cells. This conjugate is widely used in preclinical cancer research for evaluating ADC efficacy in both in vitro and in vivo models.
CAS Number
1626359-59-8
Field of Research
Pharmacology & Drug Discovery
Smiles
[H][C@@]12C[C@@] (O) (NC (=O) O1) [C@] ([H]) (OC) \C=C/C=C (C) \Cc1cc (OC) c (Cl) c (c1) N (C) C (=O) C[C@] ([H]) (OC (=O) [C@H] (C) N (C) C (=O) CCC (C) (C) SSCCC (C (=O) ON1C (=O) CCC1=O) S (O) (=O) =O) [C@]1 (C) O[C@H]1[C@@H]2C
Molecular Formula
C46H63ClN4O17S3
Molecular Weight
1075.65
Storage Conditions
-20°C
Notes
For research use only.

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