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Hydroxy bosentan

CAT: 0013-GTR19224773-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19224773-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hydroxy bosentan (Ro 48-5033) is the primary active metabolite of the endothelin receptor antagonist bosentan, formed via hepatic CYP450 metabolism. It retains approximately 10-20% of the parent drug's pharmacological activity. This metabolite is utilized in research applications investigating bosentan's pharmacokinetics, metabolic pathways, and comparative efficacy in both in vitro and in vivo experimental models.
CAS Number
253688-60-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=S (=O) (NC=1N=C (N=C (OCCO) C1OC=2C=CC=CC2OC) C3=NC=CC=N3) C4=CC=C (C=C4) C (C) (C) CO
Molecular Formula
C27H29N5O7S
Molecular Weight
567.61
Storage Conditions
-20°C
Notes
For research use only.

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