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Bosentan

CAT: 0013-GTR19172017-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19172017-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bosentan is a competitive sulfonamide-derived endothelin receptor antagonist with a preference for the ETA receptor. It inhibits the potent vasoconstrictor endothelin-1, reducing vascular resistance. It is widely used in pulmonary hypertension research and has been applied in both in vitro receptor binding assays and in vivo animal models of cardiovascular disease.
CAS Number
147536-97-8
Product Name Alternative
Benzenesulfonamide, Actelion, Bosentan, inhibit, Inhibitor, ET-A, ET-B, EndothelinReceptor, Endothelin Receptor, Ro 47-0203
Field of Research
Pharmacology & Drug Discovery
Purity
99.74% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.63 mM) ; DMSO:245 mg/mL (444.15 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:3 mg/mL (5.44 mM)
Smiles
COc1ccccc1Oc1c (NS (=O) (=O) c2ccc (cc2) C (C) (C) C) nc (nc1OCCO) -c1ncccn1
Molecular Formula
C27H29N5O6S
Molecular Weight
551.614
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
B1682-100Bosentan
B1521-200Bosentan Hydrate

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