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OARV-771

CAT: 0013-GTR19221276-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221276-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OARV-771 is a cell-permeable, VHL-based PROTAC that potently degrades BET proteins, with DC50 values of 6 nM for BRD4, 1 nM for BRD2, and 4 nM for BRD3. This molecule is a valuable chemical tool for investigating BET protein function in both cellular and in vivo models of oncology and inflammatory diseases.
CAS Number
2683008-37-7
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
C[C@H] (NC (=O) [C@@H]1C[C@@H] (O) CN1C (=O) [C@@H] (NC (=O) COCCCOCCOC (=O) C[C@@H]1N=C (c2c (C) c (C) sc2-n2c (C) nnc12) c1ccc (Cl) cc1) C (C) (C) C) c1ccc (cc1) -c1scnc1C
Molecular Formula
C49H59ClN8O8S2
Molecular Weight
987.62
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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T74391-01OARV-771
A24409-100OARV-771 100mg
A24409-50OARV-771 50mg
A24409-5OARV-771 5mg
A24409-10OARV-771 10mg
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7256/5ARV 771

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