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Gal-ARV-771

CAT: 0013-GTR19262283-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262283-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gal-ARV-771 is a PROTAC prodrug, modified with galactose, based on ARV-771. It is activated in senescent cancer cells that express SA-β-Gal, thereby releasing ARV-771. Through the ubiquitin-proteasome pathway, Gal-ARV-771 induces selective degradation of the BRD4 protein in senescent cells and promotes apoptosis (apoptosis) of these cancer cells.
Field of Research
Cell Biology, Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery
Molecular Formula
C71H84ClN9O19S2
Storage Conditions
-20°C
Notes
For research use only.

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