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KTX-951

CAT: 0013-GTR19221040-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221040-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KTX-951 is a potent IRAK4-targeting PROTAC degrader with a DC50 of 18 nM. It shows 22% oral bioavailability in rats at 10 mg/kg and exhibits promising anticancer activity in research models, supporting its investigation in oncology and inflammation-related studies.
CAS Number
2573298-36-7
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Smiles
COc1cc2nn (cc2cc1NC (=O) c1cccc (n1) C (C) (F) F) [C@H]1CC[C@H] (CN2CCC3 (CC (CCNc4cccc5C (=O) N (C6CCC (=O) NC6=O) C (=O) c45) C3) CC2) CC1
Molecular Formula
C46H52F2N8O6
Molecular Weight
850.95
Storage Conditions
-20°C
Notes
For research use only.

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