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NecroIr2

CAT: 0013-GTR19221028-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221028-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NecroIr2 is an iridium (III) complex that induces necroptosis in cisplatin-resistant A549R lung cancer cells. It localizes to mitochondria, triggering oxidative stress, loss of MMP, and activation of the RIPK3/MLKL pathway while modulating CDK4 expression, making it a useful research tool for studying programmed necrosis in drug-resistant cancers.
Field of Research
Cell Biology, Signal Transduction
Molecular Formula
C46H30ClIrN6O2-
Molecular Weight
926.44
Storage Conditions
-20°C
Notes
For research use only.

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