NecroIr1

CAT: 0013-GTR19221029-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19221029-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

NecroIr1 is an iridium (III) complex that induces necroptosis in cisplatin-resistant A549R lung cancer cells by selectively targeting mitochondria. It triggers oxidative stress, reduces MMP, and activates the RIPK3/MLKL pathway while modulating CDK4, offering a research tool for overcoming chemotherapy resistance in vitro.

Field of Research

Cell Biology, Signal Transduction

Molecular Formula

C40H29ClIrN5O-

Molecular Weight

823.36

Storage Conditions

-20°C

Notes

For research use only.