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USP28-IN-4

CAT: 0013-GTR19220920-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19220920-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
USP28-IN-4 is a potent and selective USP28 inhibitor (IC50 = 0.04 μM) that also targets several other deubiquitinases. It demonstrates anticancer activity in vitro by promoting c-Myc degradation via the proteasome, leading to cytotoxicity in colorectal and lung squamous carcinoma cell lines. This compound is a valuable chemical probe for studying USP28 biology and oncogenic pathways in cancer research.
CAS Number
2931509-15-6
Product Name Alternative
USP2, USP28, USP7, USP9x, USP8
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry
Purity
98.39% (May vary between batches)
Smiles
O=C (NC1=CC=C (Cl) C (=C1) C=2C=CC3=C (C2) CNC3) C4=CC=C (C=C4Cl) S (=O) (=O) C
Molecular Formula
C22H18Cl2N2O3S
Molecular Weight
461.36
Storage Conditions
-20°C
Notes
For research use only.

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