YL-939

• Description:

  YL-939 is a potent ferroptosis inhibitor. YL-939 inhibits ferroptosis by targeting the PHB2/ferritin/iron axis[1].

• UNSPSC:

  12352005

• Target:

  Ferroptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/yl-939.html

• Concentration:

  10mM

• Purity:

  99.03

• Solubility:

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  C1 (C2=CN3C=C (N=C (C3=N2) C4=CCOCC4) C5=CN (N=C5) C6CCNCC6) =CC=CC=C1

• Molecular Formula:

  C25H26N6O

• Molecular Weight:

  426.51

• References & Citations:

  [1]Yang W, et, al. Non-classical ferroptosis inhibition by a small molecule targeting PHB2. Nat Commun. 2022 Dec 3;13 (1) :7473.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  3023925-68-7