YL-939

• Description :

  YL-939 is a potent ferroptosis inhibitor. YL-939 inhibits ferroptosis by targeting the PHB2/ferritin/iron axis[1].

• UNSPSC :

  12352005

• Target :

  Ferroptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/yl-939.html

• Concentration :

  10mM

• Purity :

  99.03

• Solubility :

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  C1(C2=CN3C=C(N=C(C3=N2)C4=CCOCC4)C5=CN(N=C5)C6CCNCC6)=CC=CC=C1

• Molecular Formula :

  C25H26N6O

• Molecular Weight :

  426.51

• References & Citations :

  [1]Yang W, et, al. Non-classical ferroptosis inhibition by a small molecule targeting PHB2. Nat Commun. 2022 Dec 3;13 (1) :7473.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3023925-68-7]