Products for Research Use Only

GGTI-286 TFA

CAT: 0013-GTR19221622-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221622-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GGTI-286 TFA is a potent and selective cell-permeable inhibitor of GGTase I, effectively blocking Rap1A geranylgeranylation (IC50 = 2 μM) with over 15-fold selectivity against H-Ras farnesylation. It also inhibits oncogenic K-Ras4B stimulation (IC50 = 1 μM) . This compound is a valuable research tool for studying protein prenylation in cancer biology and signal transduction, both in vitro and in vivo.
Field of Research
Immunology & Inflammation
Molecular Formula
C25H32F3N3O5S
Molecular Weight
543.6
Storage Conditions
-20°C
Notes
For research use only.