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GGTI-286

CAT: 0013-GTR19186226-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19186226-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GGTI-286 is a selective geranylgeranyltransferase I (GGTase I) inhibitor with an IC50 of 2 μM. It potently blocks Rap1A geranylation in cellular models like NIH3T3 cells and is used in vitro to study the role of geranylgeranylated proteins in cancer and cardiovascular research, showing greater selectivity over farnesyltransferase.
CAS Number
171744-11-9
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (N[C@H] (C (OC) =O) CC (C) C) (=O) C1=C (C=C (NC[C@H] (CS) N) C=C1) C2=CC=CC=C2
Molecular Formula
C23H31N3O3S
Molecular Weight
429.58
Storage Conditions
-20°C
Notes
For research use only.

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