Products for Research Use Only
RegisterLogin

BMS-502

CAT: 0013-GTR19219909-05Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19219909-05Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BMS-502 is a potent dual inhibitor of DGKα and DGKζ, enhancing T cell immune responses and blocking intracellular checkpoint signaling in a dose-dependent manner. It is a valuable research tool for studying immune-related diseases in both in vitro and in vivo experimental models.
CAS Number
2407854-18-4
Product Name Alternative
BMS502, DGK
Purity
99.54% (May vary between batches)
Solubility
DMSO:80 mg/mL (154.89 mM)
Smiles
N#CC1=NC2=C (N (C) C (C ([N+] ([O-]) =O) =C2N3CCN (C (C4=CC=C (C=C4) F) C5=CC=C (C=C5) F) CC3) =O) C=C1
Molecular Formula
C27H22F2N6O3
Molecular Weight
516.5
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

8-(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)-5-methyl-7-nitro-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile
CAS Number2407854-18-4
PubChem CID146466271
IUPAC Name8-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-5-methyl-7-nitro-6-oxo-1,5-naphthyridine-2-carbonitrile
Molecular FormulaC27H22F2N6O3
Molecular Weight516.5
XLogP3.6
Topological Polar Surface Area109
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count9
Rotatable Bond Count4
Heavy Atom Count38
Formal Charge0
Complexity949
SMILES
CN1C2=C(C(=C(C1=O)[N+](=O)[O-])N3CCN(CC3)C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F)N=C(C=C2)C#N
InChI
InChI=1S/C27H22F2N6O3/c1-32-22-11-10-21(16-30)31-23(22)25(26(27(32)36)35(37)38)34-14-12-33(13-15-34)24(17-2-6-19(28)7-3-17)18-4-8-20(29)9-5-18/h2-11,24H,12-15H2,1H3
InChIKey
XAHMIJCNFUSTMT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 8-(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)-5-methyl-7-nitro-6-oxo-5,6-dihydro-1,5-naphthyridine-2-carbonitrile
CAS: 2407854-18-4
CID: 146466271
Formula: C27H22F2N6O3
MW: 516.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight516.5
XLogP33.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count9
Rotatable Bond Count4
Exact Mass516.17214491
Monoisotopic Mass516.17214491
Topological Polar Surface Area109 Ų
Heavy Atom Count38
Formal Charge0
Complexity949
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19273746-01NIP 502
GTR19200524-01BTG 502
GTR19221574-01NOSO-502
GTR19189507GNE-502
GTR19175168-01NCT-502
GTR19210430-01SPD 502
GTR19208138-01ARRY-502
GTR19194100KS 502
GTR19276170-01CRBN ligand-502
GTR17965273Let-502 Antibody

Alternative Products

CatalogName
BA7293-1BMS-502
C5478-5NCT-502
T69586-01SPD 502
HY-123922NOSO-502
HY-15074SPD-502
T23827-01BTG 502
M15690-01SUVN-502
HY-124065ARRY-502
HY-105400NIP 502
HY-132294-01GNE-502

Popular Products