Products for Research Use Only
RegisterLogin

UNC8153 TFA

CAT: 0013-GTR19219855-05Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19219855-05Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
UNC8153 TFA is a potent and selective degrader of the NSD2 protein, demonstrating anti-proliferative activity in MM.1S multiple myeloma cells. This compound serves as a valuable chemical probe for oncology research, particularly in studying epigenetic targets and protein degradation mechanisms in hematological malignancies.
CAS Number
2929304-61-8
Product Name Alternative
HistoneMethyltransferase, Histone Methyltransferase, NSD
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation
Purity
96.44% (May vary between batches)
Solubility
PBS pH 7.2:5 mg/mL (7.17 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.87 mM) ; Ethanol:30 mg/mL (43 mM) ; DMSO:30 mg/mL (43 mM) ; H2O:5 mg/mL (7.17 mM) ; DMF:30 mg/mL (43 mM)
Smiles
O=C (O) C (F) (F) F.O=C (NC1=CC=C (C=C1) C (=O) NCCCCCCN) C2=CC=C (C=C2) CN (C (=O) C3=CC=C4NC (=O) COC4=C3) C5CC5
Molecular Formula
C35H38F3N5O7
Molecular Weight
697.7
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

UNC8153 (trifluoroacetate salt)
CAS Number2929304-61-8
PubChem CID169492943
IUPAC NameN-[[4-[[4-(6-aminohexylcarbamoyl)phenyl]carbamoyl]phenyl]methyl]-N-cyclopropyl-3-oxo-4H-1,4-benzoxazine-7-carboxamide;2,2,2-trifluoroacetic acid
Molecular FormulaC35H38F3N5O7
Molecular Weight697.7
Topological Polar Surface Area180
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count11
Rotatable Bond Count13
Heavy Atom Count50
Formal Charge0
Complexity1040
SMILES
C1CC1N(CC2=CC=C(C=C2)C(=O)NC3=CC=C(C=C3)C(=O)NCCCCCCN)C(=O)C4=CC5=C(C=C4)NC(=O)CO5.C(=O)(C(F)(F)F)O
InChI
InChI=1S/C33H37N5O5.C2HF3O2/c34-17-3-1-2-4-18-35-31(40)23-9-12-26(13-10-23)36-32(41)24-7-5-22(6-8-24)20-38(27-14-15-27)33(42)25-11-16-28-29(19-25)43-21-30(39)37-28;3-2(4,5)1(6)7/h5-13,16,19,27H,1-4,14-15,17-18,20-21,34H2,(H,35,40)(H,36,41)(H,37,39);(H,6,7)
InChIKey
PRNFABQCXAELBV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of UNC8153 (trifluoroacetate salt)
CAS: 2929304-61-8
CID: 169492943
Formula: C35H38F3N5O7
MW: 697.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight697.7
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count11
Rotatable Bond Count13
Exact Mass697.27233305
Monoisotopic Mass697.27233305
Topological Polar Surface Area180 Ų
Heavy Atom Count50
Formal Charge0
Complexity1040
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19233827-01UNC8153
GTR19221711-01Albiglutide TFA
GTR19221625-01Homocarnosine TFA
GTR19221513-01Mifamurtide TFA
GTR19220144-01Chlorotoxin TFA
GTR19220136-01FC131 TFA
GTR19219465-01Elarofiban TFA
GTR19213644-01Traxanox TFA
GTR19213125Aβ-IN-1 TFA
GTR19209198-01Afegostat TFA

Alternative Products

CatalogName
T88389-01UNC8153
A24332-5UNC8153 5mg
A24332-50UNC8153 50mg
A24332-10UNC8153 10mg
BUP01467-01UNC8153 TFA
HY-157251-01UNC8153 (TFA)
A24332-1UNC8153 1mg

Popular Products