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RET-IN-22

CAT: 0013-GTR19219493-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219493-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RET-IN-22 (compound 17b) is a potent, selective, and orally bioavailable RET inhibitor with IC50 values of 20.9 nM (wild-type) and 18.3 nM (RET-V804M) . It shows high selectivity over kinases like EGFR and VEGFR2. This inhibitor is used in preclinical cancer research to study RET-driven tumors in both cellular and animal models.
CAS Number
2918281-79-3
Field of Research
Cell Biology, Signal Transduction
Smiles
N (C (NC=1C=C (C (C (F) (F) F) (C) C) ON1) =O) C2=CC=C (C=3C=C (NN3) C4=CC=C (OCCN5CCOCC5) C=C4) C=C2
Molecular Formula
C29H31F3N6O4
Molecular Weight
584.59
Storage Conditions
-20°C
Notes
For research use only.

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