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MHTT-IN-2

CAT: 0013-GTR19218965Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218965Size:5 mg
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Description
MHTT-IN-2 is a potent small molecule splicing modulator that selectively reduces mutant huntingtin (mHTT) with an EC50 of 66 nM. It has demonstrated efficacy in both human Huntington's disease stem cells and BACHD mouse models, supporting its use in preclinical research for HD and related neuropathies.
CAS Number
2743336-70-9
Field of Research
Neuroscience
Smiles
FC=1C=2N (C=C (NC (=O) C=3C=NC (=CN3) N4C[C@H] (NC5CC5) CC4) C1) C=C (C) N2
Molecular Formula
C20H22FN7O
Molecular Weight
395.43
Storage Conditions
-20°C
Notes
For research use only.

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