Products for Research Use Only
RegisterLogin

Thalidomide-NH-C6-NH2 TFA

CAT: 0013-GTR19224853-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19224853-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This synthetic E3 ligase ligand-linker conjugate incorporates a Thalidomide-based cereblon ligand and a PROTAC linker. It serves as a key component for constructing PROTAC molecules, enabling targeted protein degradation research in both cellular and biochemical assays.
CAS Number
2093386-51-5
Field of Research
Cell Biology, Immunology & Inflammation; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery
Smiles
O=C (O) C (F) (F) F.O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCCCCCCN) C3C2=O) CC1
Molecular Formula
C21H25F3N4O6
Molecular Weight
486.44
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Thalidomide-NH-C6-NH2 TFA
CAS Number2093386-51-5
PubChem CID146047127
IUPAC Name4-(6-aminohexylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;2,2,2-trifluoroacetic acid
Molecular FormulaC21H25F3N4O6
Molecular Weight486.4
Topological Polar Surface Area159
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count11
Rotatable Bond Count8
Heavy Atom Count34
Formal Charge0
Complexity692
SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCCCCCN.C(=O)(C(F)(F)F)O
InChI
InChI=1S/C19H24N4O4.C2HF3O2/c20-10-3-1-2-4-11-21-13-7-5-6-12-16(13)19(27)23(18(12)26)14-8-9-15(24)22-17(14)25;3-2(4,5)1(6)7/h5-7,14,21H,1-4,8-11,20H2,(H,22,24,25);(H,6,7)
InChIKey
VUTCFPKPHCMKEA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Thalidomide-NH-C6-NH2 TFA
CAS: 2093386-51-5
CID: 146047127
Formula: C21H25F3N4O6
MW: 486.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight486.4
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count11
Rotatable Bond Count8
Exact Mass486.17261902
Monoisotopic Mass486.17261902
Topological Polar Surface Area159 Ų
Heavy Atom Count34
Formal Charge0
Complexity692
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19224852-01Thalidomide-NH-C6-NH2
GTR19261164-01Thalidomide-NH-amido-C6-NH2
GTR19216484-01Thalidomide-NH-C6-NH2 hydrochloride
GTR19170085Thalidomide-NH-C6-NH2 hydrochloride
GTR19215623-01Thalidomide-O-C6-NH2 TFA
GTR19224854-01Thalidomide-NH-C4-NH2 TFA
GTR19276479-01Thalidomide-NH-C5-NH2 TFA
GTR19240319-01N-Me-Thalidomide-NH-C6-NH2
GTR19261165-01Thalidomide-NH-amido-C6-NH2 hydrochloride
GTR19178096-01Thalidomide-O-amido-C6-NH2 TFA

Alternative Products

CatalogName
HY-129704Thalidomide-NH-C6-NH2
T208134-01Thalidomide-NH-amido-C6-NH2
HY-129704A-01Thalidomide-NH-C6-NH2 (TFA)
HY-129704B-01Thalidomide-NH-C6-NH2 (hydrochloride)
MBS3616815-01Thalidomide-NH-C6-NH2 hydrochloride
MBS5771667Thalidomide-NH-C6-NH2 TFA
HY-138852AThalidomide-NH-amido-C6-NH2 (hydrochloride)
T208135-01Thalidomide-NH-amido-C6-NH2 hydrochloride
HY-170337N-Me-Thalidomide-NH-C6-NH2
BA3163-100Thalidomide-NH-C6-NH-Boc

Popular Products