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EP12

CAT: 0013-GTR19218860-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218860-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EP12 is a small molecule that inhibits c-Myc and stabilizes G-quadruplex (G4) DNA, triggering apoptosis and DNA damage in multiple myeloma cells. It suppresses tumor growth by blocking the NF-κB pathway, preventing P65/P50 nuclear translocation, as demonstrated in in vitro and in vivo oncology research.
CAS Number
2882916-73-4
Field of Research
Cell Biology
Smiles
C (COC1=CC (C) =CC (C) =C1) N2C (=NC=3C2=CC=CC3) C=4C=C (ON4) C5=CC=C (F) C=C5
Molecular Formula
C26H22FN3O2
Molecular Weight
427.47
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

3-[1-[2-(3,5-Dimethylphenoxy)ethyl]benzimidazol-2-yl]-5-(4-fluorophenyl)-1,2-oxazole
CAS Number2882916-73-4
PubChem CID167440360
IUPAC Name3-[1-[2-(3,5-dimethylphenoxy)ethyl]benzimidazol-2-yl]-5-(4-fluorophenyl)-1,2-oxazole
Molecular FormulaC26H22FN3O2
Molecular Weight427.5
XLogP5.7
Topological Polar Surface Area53.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count32
Formal Charge0
Complexity592
SMILES
CC1=CC(=CC(=C1)OCCN2C3=CC=CC=C3N=C2C4=NOC(=C4)C5=CC=C(C=C5)F)C
InChI
InChI=1S/C26H22FN3O2/c1-17-13-18(2)15-21(14-17)31-12-11-30-24-6-4-3-5-22(24)28-26(30)23-16-25(32-29-23)19-7-9-20(27)10-8-19/h3-10,13-16H,11-12H2,1-2H3
InChIKey
QBDKHCSVTPBJGK-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-[1-[2-(3,5-Dimethylphenoxy)ethyl]benzimidazol-2-yl]-5-(4-fluorophenyl)-1,2-oxazole
CAS: 2882916-73-4
CID: 167440360
Formula: C26H22FN3O2
MW: 427.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight427.5
XLogP35.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass427.16960512
Monoisotopic Mass427.16960512
Topological Polar Surface Area53.1 Ų
Heavy Atom Count32
Formal Charge0
Complexity592
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
HY-149513EP12
CCR-1142-01Cyclin D1 (EP12), RMab
TT-EP12-200UElitePro Multi-Channel Adjustable Volume Pipette TT-EP12-200U, 20-200µL
TT-EP12-10UElitePro Multi-Channel Adjustable Volume Pipette TT-EP12-10U, 1-10µL
TT-EP12-300UElitePro Multi-Channel Adjustable Volume Pipette TT-EP12-300U, 30-300µL
TT-EP12-50UElitePro Multi-Channel Adjustable Volume Pipette TT-EP12-50U, 5-50µL
TT-EP12-20UElitePro Multi-Channel Adjustable Volume Pipette TT-EP12-20U, 2-20µL

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