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EP12

CAT: 0931-T78846-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T78846-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2882916-73-4
Target
Apoptosis, c-Myc
Related Pathways
Apoptosis, Cell Cycle/Checkpoint
Bioactivity
EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by disrupting the NF-κB signaling pathway, effectively inhibiting multiple myeloma growth [1].
Smiles
C(COC1=CC(C)=CC(C)=C1)N2C(=NC=3C2=CC=CC3)C=4C=C(ON4)C5=CC=C(F)C=C5
Molecular Formula
C26H22FN3O2
Molecular Weight
427.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C