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TLR7/8 agonist 9

CAT: 0013-GTR19218786-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218786-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Compound 25a is a potent dual TLR7/8 agonist with EC50 values of 40 nM (hTLR7) and 23 nM (hTLR8) . It exhibits anti-tumor activity and can synergize with PD-1/PD-L1 blockade in cancer immunotherapy research, as supported by studies in both cellular assays and animal models.
CAS Number
2649170-17-0
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology
Smiles
N (CCOC) C=1C2=C (C=CC (CC3=CC=C (CN (C) C) C=C3) =N2) N=C (N) N1
Molecular Formula
C20H26N6O
Molecular Weight
366.46
Storage Conditions
-20°C
Notes
For research use only.

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