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MK-2206 free base

CAT: 0013-GTR19218499-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218499-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MK-2206 free base is a potent, selective, and orally active allosteric Akt inhibitor with IC50 values of 8, 12, and 65 nM for Akt1, Akt2, and Akt3, respectively. It shows activity in breast cancer models with PIK3CA mutations or PTEN loss and has been investigated in both in vitro and in vivo preclinical studies.
CAS Number
1032349-93-1
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C1NN=C2C=3C=C (C=4C=CC=CC4) C (=NC3C=CN12) C=5C=CC (=CC5) C6 (N) CCC6
Molecular Formula
C25H21N5O
Molecular Weight
407.47
Storage Conditions
-20°C
Notes
For research use only.

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