Products for Research Use Only

CC-3060

CAT: 0013-GTR19218082-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218082-01Size:5 mg
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Description
CC-3060 is a potent and selective Cereblon modulator that induces the targeted degradation of ZBTB16 with a DC50 of 0.47 nM in HT-1080 cells. It is a valuable chemical probe for studying zinc finger protein function in cancer research, including applications in leukemia models both in vitro and in vivo.
CAS Number
444288-86-2
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCC=4OC=5C=CC=CC5C4) C3C2=O) CC1
Molecular Formula
C22H17N3O5
Molecular Weight
403.39
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4-(1-Benzofuran-2-ylmethylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
CAS Number444288-86-2
PubChem CID21988575
IUPAC Name4-(1-benzofuran-2-ylmethylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Molecular FormulaC22H17N3O5
Molecular Weight403.4
XLogP2.6
Topological Polar Surface Area109
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count30
Formal Charge0
Complexity755
SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCC4=CC5=CC=CC=C5O4
InChI
InChI=1S/C22H17N3O5/c26-18-9-8-16(20(27)24-18)25-21(28)14-5-3-6-15(19(14)22(25)29)23-11-13-10-12-4-1-2-7-17(12)30-13/h1-7,10,16,23H,8-9,11H2,(H,24,26,27)
InChIKey
GRICLJZNEMDVMA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-(1-Benzofuran-2-ylmethylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
CAS: 444288-86-2
CID: 21988575
Formula: C22H17N3O5
MW: 403.4
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight403.4
XLogP32.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass403.11682065
Monoisotopic Mass403.11682065
Topological Polar Surface Area109 Ų
Heavy Atom Count30
Formal Charge0
Complexity755
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes