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Gypenoside XLIX

CAT: 0804-HY-N1990-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1990-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gypenoside XLIX, a dammarane-type glycoside, is a prominent component of G. pentaphyllum. Gypenoside XLIX is a selective peroxisome proliferator-activated receptor (PPAR) -alpha activator and inhibits cytokine-induced vascular cell adhesion molecule-1 (VCAM-1) overexpression and hyperactivity in human endothelial cells[1].
CAS Number
94987-08-3
UNSPSC
12352005
Target
PPAR
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gypenoside-xlix.html
Purity
99.99
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C[C@@]([C@](CC1)([H])C2(C)C)(CC[C@@H]2O[C@@](OC[C@H](O)[C@@H]3O[C@@](OC[C@@H](O)[C@@H]4O)([H])[C@@H]4O)([H])[C@@H]3O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)[C@](CC[C@@]6([H])[C@]7(CC[C@]6([H])[C@](CC/C=C(C)/C)(O)CO[C@@H]([C@@H]([C@@H](O)[C@@H]8O)O)O[C@@H]8CO)C)([H])[C@]71C
Molecular Formula
C52H86O21
Molecular Weight
1047.23
References & Citations
[1]Huang TH , et al. Gypenoside XLIX, a naturally occurring PPAR-alpha activator, inhibits cytokine-induced vascular cell adhesion molecule-1 expression and activity in human endothelial cells. Eur J Pharmacol. 2007 Jun 22;565 (1-3) :158-65.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
PPARα

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