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Gypenoside A

CAT: 0804-HY-N2440-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2440-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gypenoside A is an orally active triterpenoid compound that can be isolated from Gynostemma pentaphyllum. Gypenoside A has anti-inflammatory and antioxidant activities. Gypenoside A also has a certain protective effect on cardiomyocytes and can inhibit apoptosis. Gypenoside A can be used in the research of cardiovascular diseases and inflammation-related diseases[1][2][3].
CAS Number
157752-01-7
UNSPSC
12352005
Target
AMPK; Apoptosis; COX; FOXO; Interleukin Related; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Epigenetics; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gypenoside-a.html
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=CC12C3C(C4(C(C(C5(CC(/C=C(C)/C)OC5O)O)CC4)CC3)C)(CCC1C(C)(C(OC6C(C(C(O)CO6)OC7C(C(C(O)CO7)O)O)OC8C(C(C(O)C(C)O8)O)O)CC2)C)C
Molecular Formula
C46H74O17
Molecular Weight
899.07
References & Citations
[1]Huang WC, et al. Gypenoside A from Gynostemma pentaphyllum Attenuates Airway Inflammation and Th2 Cell Activities in a Murine Asthma Model. Int J Mol Sci. 2022 Jul 12;23 (14) :7699.|[2]He Y, et al. Determination of Gypenoside A and Gypenoside XLIX in Rat Plasma by UPLC-MS/MS and Applied to the Pharmacokinetics and Bioavailability. Int J Anal Chem. 2022 Aug 12;2022:6734408.|[3]Chang L, et al. Gypenoside A protects ischemia/reperfusion injuries by suppressing miR-143-3p level via the activation of AMPK/Foxo1 pathway. Biofactors. 2020 May;46 (3) :432-440.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
FOXO1; IL-13; IL-4; IL-5; IL-6

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CatalogName
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CatalogName
M18086-01Gypenoside A
M22119-01Gypenoside L
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XG171342-01Gypenoside Li
T2S1593-01Gypenoside XLVI
380417Gypenoside XIII
T3385-01Gypenoside XVII
300392Gypenoside XLIX
MBS5791915Gypenoside LVII
MBS5785396Gypenoside LXXV

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