Cyfluthrin

CAT: 0013-GTR19216510-01Size: 1 gDry Ice: NoHazardous: No

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CAT#:0013-GTR19216510-01Size:1 g

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Description

Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests. (In Vitro) :Cell viability MTT assay was carried out to assess cyfluthrin cytotoxicity; IC30 and IC50 values for cyfluthrin were calculated to be 4.81 ± 0.92 μM and 19.39 ± 3.44 μM, respectively. Cyfluthrin increased significantly gene expressions of apoptosis, proinflammation and oxidative stress (Bax, Bcl-2, Casp-3, BNIP3, AKT1, p53, APAF1, NFκB1, TNFα and Nrf2) mediators. In the most genes, the mRNA levels induced by cyfluthrin were partially reduced by MEL (1 μM) .

CAS Number

68359-37-5

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Smiles

CC1 (C) C (C=C (Cl) Cl) C1C (=O) OC (C#N) c1ccc (F) c (Oc2ccccc2) c1

Molecular Formula

C22H18Cl2FNO3

Molecular Weight

434.29

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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Cyfluthrin

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