Cyfluthrin-d6

Cyfluthrin-d6

• CAS Number: 2483831-11-2
• UNSPSC Description: Cyfluthrin-d6 (β-Cyfluthi-d6) is deuterium labeled Cyfluthrin. Cyfluthrin is a type II pyrethroid and has effects on various insects. Cyfluthrin is a modulator of Nav1.8 sodium channels by repetitive stimulation. Cyfluthrin can be applied in agriculture,veterinary, insecticide,pyrethroid and stored product[1][2].
• Target Antigen: Isotope-Labeled Compounds; Sodium Channel
• Type: Isotope-Labeled Compounds
• Related Pathways: Membrane Transporter/Ion Channel;Others
• Field of Research: Infection
• Smiles: N#CC(C1=CC(OC2=CC=CC=C2)=C(C=C1)F)OC(C3C(C3(C([2H])([2H])[2H])C([2H])([2H])[2H])/C=C(Cl)\Cl)=O
• Molecular Weight: 440.32
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Jin-Sung Choi,et al.Structure-activity Relationships for the Action of 11 Pyrethroid Insecticides on Rat Na v 1.8 Sodium Channels Expressed in Xenopus Oocytes.Toxicol Appl Pharmacol. 2006 Mar 15;211(3):233-44|[3]María-Aránzazu Martínez, et al. Oxidative Stress and Related Gene Expression Effects of Cyfluthrin in Human Neuroblastoma SH-SY5Y Cells: Protective Effect of Melatonin. Environ Res. 2019 Oct;177:108579.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported